A practical early factory layout puts linked machines in processing order, keeps belt runs easy to follow, and reserves a clear side for expansion. Use that plan for the first station before deciding where a specialized outpost makes more sense.
Sketch a straight path for your first product
Start with the supply point and work toward the finished output. Line up the machines that feed each other. When a product needs a second ingredient, bring it in from the side so you can inspect both feeds without tracing a tangled run.
Reserve room for a parallel line
Keep an open edge beside the process that is most likely to grow. If you add a second machine later, you can connect it to the same supply area while keeping its output visible. The best use of this space depends on the product you want more of.
Separate production when transport earns its keep
Once a line runs reliably, compare extending it locally with building a dedicated supply site. Main Sequence supports automated routes between stations, so a separate facility can make sense once you can verify both loading and receiving.
See Main Sequence on Steam for the official game information.
FAQ
Is a straight line always best?
It is a useful starting layout because each handoff stays visible. Choose a different shape when your available space or inputs call for it.
What usually deserves space for expansion?
Reserve room beside the input or processing stage you expect to duplicate.
Can stations specialize?
Yes. The game supports supply routes between stations, which lets a fleet connect facilities with different jobs.